Caffeine is one of the most comprehensively studied ingredients in the food supply. There is considerable knowledge of this compound, with centuries of safe consumption in foods and beverages. However, questions and misperceptions about potential health effects associated with caffeine persist, including those centering on hydration, addiction, miscarriage, osteoporosis, and consumption by children and teenagers. Additionally, with the wave of new products containing caffeine entering the marketplace, caffeine is increasingly in the media spotlight. The following science-based, informational resources are useful for consumers, health professionals, and the media in providing balance and insight regarding caffeine and health.